Disease

How to play Disease by Lady Gaga on guitar

These are the sounding chords. With a capo on fret 7 you play E, G, C, A, Em, D and more, the shapes the player above shows.

Disease is a strong song to learn if you want a driving, modern feel with a steady pulse. It sits well at about 120 BPM, so once you lock into the groove it feels energetic and controlled rather than rushed.

You can lean on the open shapes D, G, E, A, and Am for most of the comfort, but the B and Bm shapes are the harder moves to prepare for. The main change to watch is the opening B - D - G - E motion, since that shift from a barre shape into open chords can feel abrupt at first.

Start by looping B - D - G - E slowly until your hands stop hesitating, then practice each shape cleanly on its own. Next, connect the open chords in smaller groups, and only after that bring the full progression up to tempo. Keep the changes even and let speed come from repetition.

Use the play-along above to follow each chord change in time with the music, or learn the shapes first with the chord diagrams below.